eznews.inA recent study from the Universities of York and East Anglia highlights the critical role of sleep in regulating our ability to suppress intrusive memories, which is essential for mental health. Researchers found that disrupted sleep impairs the brain's capacity to inhibit unwanted thoughts, potentially increasing vulnerability to conditions such as anxiety, depression, and post-traumatic stress disorder (PTSD). The study involved 85 participants who underwent functional MRI scans to observe brain activity during memory suppression tasks after a night of either sleep or sleep deprivation. Results indicated that those who had not slept exhibited reduced activity in the right dorsolateral prefrontal cortex, a region linked to emotional regulation. The findings suggest that improving sleep hygiene could enhance memory suppression capabilities and mitigate the risk of developing mental health issues. Experts emphasize the importance of cultivating good sleep habits to support emotional regulation and overall mental well-being. 
Published: Jan 25 2025, 1 pmeznews.inNew research suggests that drinking carbonated or sparkling water may contribute to weight loss by enhancing glucose metabolism and red blood cell function. A report published in *BMJ Nutrition, Prevention & Health* indicates that the carbon dioxide (CO2) in sparkling water can increase glucose uptake in red blood cells, potentially lowering blood sugar levels. However, the findings highlight that the weight loss effects are minimal and should not be considered a standalone solution. The study emphasizes the need for further research, particularly clinical trials comparing carbonated and non-carbonated water. Experts caution that while sparkling water may offer some health benefits, including temporary relief from constipation, it can also lead to digestive issues such as bloating and gas. Overall, a balanced diet and regular exercise remain essential for effective weight management, and moderation in sparkling water consumption is advised.
Published: Jan 25 2025, 2 ameznews.inWearable devices, such as the Apple Watch and Fitbit, may soon offer a groundbreaking advance in managing inflammatory bowel disease (IBD) by predicting flare-ups up to seven weeks in advance, according to a study from Mount Sinai researchers. The study, involving 309 participants with Crohn's disease or ulcerative colitis, identified significant physiological changes—such as variations in heart rate, resting heart rate, heart rate variability, physical activity, and blood oxygen levels—that precede flare-ups. This early warning could empower patients to adjust medications or diets proactively, potentially mitigating symptoms before they occur. Dr. Rudolph Bedford emphasized the unpredictability of IBD, highlighting the need for such predictive tools. The study's lead author, Dr. Robert Hirten, noted that these findings could extend beyond IBD to other chronic inflammatory conditions, with aspirations to develop AI algorithms for personalized flare prediction systems.
Published: Jan 25 2025, 12 ameznews.inIntermittent fasting, particularly an "early" time-restricted eating pattern, is gaining attention for its potential health benefits, including weight loss and improved metabolic health. A recent study published in *Nature Medicine* involved nearly 200 participants aged 30 to 60 with a BMI over 32, who were assigned to different fasting groups. Those in the early fasting group, consuming food between 9:45 AM and 5:30 PM, experienced greater reductions in abdominal fat and improved blood sugar levels compared to other groups. Lead researcher Jonatan R. Ruiz emphasized that aligning eating with the body’s circadian rhythms may enhance metabolic efficiency. While all fasting groups lost an average of 3-4 kg, the early group showed the most significant benefits. Experts suggest further research to explore the long-term effects of this dietary approach and its integration with exercise for optimal health outcomes.
Published: Jan 24 2025, 1 ameznews.inA recent study from Brigham and Women’s Hospital and Harvard Medical School reveals that intramuscular fat—fat stored within muscle tissue—may pose a greater risk for heart disease than subcutaneous fat, even among individuals with a healthy weight. Published in the *European Heart Journal*, the research tracked 669 participants over six years, finding that those with higher levels of intramuscular fat were more likely to develop coronary microvascular dysfunction and face increased risks of hospitalization or death due to heart disease. Specifically, for every 1% increase in intramuscular fat, the risk of serious heart disease rose by 7%. The study highlights the importance of fat distribution in assessing heart health, suggesting that traditional measures like BMI may not adequately reflect an individual's risk. Researchers aim to explore how lifestyle changes and new therapies can mitigate the impacts of fatty muscle on heart health.
Published: Jan 23 2025, 11 pmeznews.inA recent study published in *Nature Aging* has shed light on the heightened risk of osteoarthritis in postmenopausal women, linking it to hormonal changes during menopause. Researchers found that a drop in key hormones, 17beta-estradiol and progesterone, led to increased cartilage degeneration and joint inflammation in chemically induced menopausal mice. The study revealed that hormone replacement therapy with these hormones improved cartilage integrity and gait in the mice. However, the research also highlighted the need for caution, as findings from mouse models may not fully translate to humans. Experts emphasize that further research is necessary to explore the implications for hormone replacement therapy in treating or preventing osteoarthritis in postmenopausal women. The study's authors aim to develop targeted treatments for osteoarthritis and other menopause-related musculoskeletal disorders, potentially improving the quality of life for millions affected by this debilitating condition.
Published: Jan 22 2025, 11 pmeznews.inA recent systematic review led by researchers from the University of Cambridge and the University of Exeter suggests that common treatments, including anti-inflammatory drugs like ibuprofen, antibiotics, antiviral medications, and vaccines, may be linked to a lower risk of dementia. With over 55 million people affected globally, dementia, particularly Alzheimer's disease, poses a significant health challenge, costing more than $1 trillion annually. While the review highlights potential benefits, experts caution against hastily repurposing these medications for dementia treatment without further research. They emphasize the need for large-scale, longitudinal studies to clarify which specific drugs might effectively reduce dementia risk and to account for individual genetic and lifestyle factors. Despite the promising findings, neurologists stress that lifestyle changes remain the most effective strategy for reducing dementia risk, urging individuals to consult specialists for tailored medication advice.
Published: Jan 22 2025, 9 pmeznews.inA recent study published in *Nature Medicine* highlights the dual nature of GLP-1 receptor agonists, widely used for weight loss. While these medications have been linked to significant neurological and behavioral health benefits, including reduced risks of dementia and addiction, they also pose potential health risks. Researchers analyzed data from over 2 million patients, revealing that GLP-1 users experienced a decreased risk of cognitive decline but faced increased chances of gastrointestinal issues, pancreatitis, and kidney problems. Dr. Ziyad Al-Aly, the study's senior author, emphasized the need for awareness of these side effects among patients and healthcare providers. Experts like Dr. Babak Firoozi noted the promising cognitive benefits, while Dr. Seth Kipnis pointed out the importance of nutritional education to mitigate risks. As the popularity of GLP-1 medications grows, understanding their comprehensive health impacts remains crucial.
Published: Jan 21 2025, 11 pmeznews.inThe American Academy of Neurology has unveiled a 12-question checklist aimed at enhancing brain health, encouraging individuals to engage in proactive discussions with their healthcare providers. This initiative, detailed in the medical journal *Neurology*, highlights essential factors such as sleep, diet, exercise, and mental well-being, collectively termed "SAFEST BRAINS." Experts emphasize the importance of consistency in maintaining healthy habits, with recommendations including regular exercise, quality sleep, and mental health practices like meditation. Neurologists Jasmin Dao and Vernon Williams stress that addressing issues like excessive screen time and ensuring supportive social interactions can significantly benefit cognitive function. They advocate for making brain health a priority in personal resolutions, asserting that it is never too late to adopt positive changes that can enhance overall quality of life.
Published: Jan 21 2025, 3 pmeznews.inA recent study published in *Cancer Discovery* has identified a protein, PIN1, that promotes bladder cancer by triggering cholesterol synthesis in cancer cells. Researchers found that a combination therapy using the statin simvastatin and a PIN1 inhibitor, sulfopin, effectively suppresses tumor growth by disrupting this cholesterol production pathway. Bladder cancer is the fourth most common cancer diagnosed in men in the U.S. and often goes under-researched despite its significant impact. Current treatments such as chemotherapy and immune therapies are not fully effective, highlighting an urgent need for new therapeutic approaches. The findings suggest that targeting PIN1 may offer a viable treatment strategy not only for bladder cancer but potentially for other cancers where PIN1 is implicated. Experts emphasize the importance of continued research to uncover novel treatment mechanisms that could better manage or cure bladder cancer, which often requires extensive surgical intervention and incurs high treatment costs.
Published: Jan 20 2025, 11 pmFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
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