eznews.inA recent study published in PNAS highlights that reducing caloric intake, particularly from ultra-processed foods, may be more crucial for weight loss than increasing physical activity. Over the past three decades, obesity rates have surged globally, with the World Health Organization attributing 3.7 million deaths in 2021 to high body mass index (BMI) linked to noncommunicable diseases. Researchers analyzed data from 4,213 adults across diverse populations, finding that while energy expenditure was greater in economically developed areas, excessive calorie consumption remained the primary factor in rising obesity levels. Experts emphasize that ultra-processed foods, designed to be hyper-palatable, contribute significantly to overconsumption and higher body fat percentages. They advocate for policy measures to promote healthier food choices and encourage physical activity, underscoring that the quality of calories consumed may be as important, if not more so, than the quantity. 
Published: Jul 19 2025, 12 ameznews.inScientists in Australia have developed a groundbreaking weekly injectable treatment for Parkinson's disease, which affects over 10 million people globally, predominantly those over 50. This new long-acting implant combines levodopa and carbidopa, two medications traditionally taken in pill form multiple times a day to manage symptoms such as tremors, stiffness, and movement issues. The injectable form, which releases the drugs over seven days, could significantly ease the daily medication burden for patients. Initial studies suggest the implant is easy to inject and effectively releases up to 90% of the medication within a week. However, experts caution that further research is needed to assess safety and efficacy in humans, as well as to address potential dosing challenges and side effects. If successful, this innovative treatment could transform the management of Parkinson's, enhancing the quality of life for many patients.
Published: Jul 18 2025, 8 pmeznews.inThe World Health Organization (WHO) has recommended lenacapavir, an injectable medication, as a new preventive measure against HIV, following successful trials demonstrating its efficacy. Originally developed for treating HIV, lenacapavir, marketed as Sunlenca and now Yeztugo, has shown nearly 100% effectiveness in preventing new infections when administered twice yearly. This recommendation comes amid ongoing global challenges with HIV, which saw approximately 1.3 million new diagnoses and 630,000 related deaths in a recent year. Lenacapavir's unique properties allow it to disrupt multiple stages of the HIV life cycle, making it a promising option for individuals struggling with adherence to daily oral medications. Experts emphasize that lenacapavir could significantly enhance prevention efforts, particularly in regions where stigma and accessibility hinder current prevention strategies. The WHO's guidelines also stress the importance of equitable access to the new treatment to maximize its impact on public health.
Published: Jul 17 2025, 5 pmeznews.inA recent study has revealed that dietary patterns, particularly the Mediterranean and MIND diets, may significantly reduce the risk of dementia in older adults, especially women. Utilizing data from the UK Biobank, researchers assessed the eating habits of 131,209 participants over an average follow-up period of 13.5 years. Their findings indicated that adherence to healthy diets was linked to a lower incidence of dementia, while pro-inflammatory diets increased risk. Notably, participants who closely followed the Mediterranean diet experienced a 24% reduction in dementia risk. The study also highlighted that dietary impacts were more pronounced in women and older individuals, suggesting that healthcare professionals should prioritize discussions about brain-healthy diets with patients. However, researchers acknowledged limitations, including reliance on self-reported dietary data and the study's lack of diversity, emphasizing the need for further research to explore dietary changes over time and their long-term effects on dementia risk.
Published: Jul 16 2025, 11 pmeznews.inA recent study published in the *Journal of Regional Anesthesia & Pain Medicine* has highlighted a concerning link between prolonged gabapentin use for lower back pain and an increased risk of cognitive impairment and dementia. Researchers analyzed data from over 26,000 adults and found that those receiving six or more prescriptions of gabapentin faced a 29% higher risk of developing dementia and an 85% greater likelihood of being diagnosed with mild cognitive impairment (MCI), particularly among adults aged 35 to 49, where risks more than doubled. While gabapentin is commonly prescribed for seizures and nerve pain, the findings prompt calls for further investigation into its long-term cognitive effects. Experts recommend that physicians closely monitor patients on gabapentin for any signs of cognitive decline and encourage patients to report any cognitive deficits. The study underscores the importance of cautious prescribing practices amid growing concerns over the medication's potential side effects.
Published: Jul 16 2025, 5 pmeznews.inNew research from the German Institute of Human Nutrition suggests that eating late in the evening may impair blood sugar control, potentially contributing to obesity and heart disease. The study, which analyzed data from a twin study conducted in 2009-2010, indicates that individuals who consume their last meal closer to bedtime exhibit lower insulin sensitivity, suggesting a link between meal timing and glucose metabolism. This aligns with the understanding that our metabolism operates differently throughout the day, influenced by our circadian rhythms. However, experts like registered dietitian Destini Moody caution against overemphasizing meal timing for weight or blood sugar management, especially in healthy individuals without metabolic disorders. She stresses the importance of a balanced diet rich in fiber, whole grains, and lean proteins to maintain overall health and mitigate risks associated with refined carbohydrates. The findings highlight the complex interplay between eating habits, internal biological clocks, and metabolic health.
Published: Jul 16 2025, 1 ameznews.inResearchers are exploring psilocybin, the active compound in psychedelic mushrooms, as a potential anti-aging therapy. A recent study published in the journal *NPJ Aging* indicates that psilocybin may significantly extend the lifespan of human skin and lung cells by over 50%. The findings suggest that psilocybin could also protect against age-related diseases, including neurodegeneration and cancer, by reducing oxidative stress and preserving telomere length. In experiments with mice equivalent to 60-65 human years, those treated with psilocybin exhibited longer lifespans and healthier features. Louise Hecker, the study's senior author, emphasized the need for further research to understand psilocybin's systemic effects and to establish protocols for clinical use. While experts acknowledge the promising nature of these findings, they caution that more studies are necessary to determine the implications for human health and aging.
Published: Jul 15 2025, 11 pmeznews.inA recent study published in the journal *Menopause* highlights the critical link between menopausal health and cardiovascular risks, finding that only 20% of menopausal women achieve ideal scores on the American Heart Association’s health assessment tool, Life’s Essential 8 (LE8). Researchers, led by Dr. Samar R. El Khoudary from the University of Pittsburgh, analyzed data from approximately 3,000 women and identified four key factors—blood sugar control, blood pressure management, sleep quality, and nicotine use—as pivotal for future heart health. The study emphasizes the physiological changes during menopause, including increased visceral fat and vascular stiffness, which can exacerbate heart disease risks. Experts stress the importance of addressing these factors through public health initiatives and targeted interventions to improve cardiovascular outcomes for women in midlife, particularly focusing on enhancing sleep quality and managing other lifestyle factors that contribute to heart health.
Published: Jul 14 2025, 11 pmeznews.inA recent study from The First Affiliated Hospital of Zhengzhou University in China has highlighted the benefits of calorie restriction for weight loss and blood sugar control in individuals with obesity and type 2 diabetes. Presented at the ENDO 2025 conference, the study evaluated three dietary approaches: Intermittent Energy Restriction (IER), Time-Restricted Eating (TRE), and Continuous Energy Restriction (CER). All methods resulted in weight loss and improved blood glucose levels, with IER showing slightly greater effectiveness in reducing fasting blood glucose and improving insulin sensitivity. Participants lost an average of 7.5 kg, with a notable reduction in HbA1c levels. Experts recommend individuals choose the method that best fits their lifestyle, emphasizing the importance of adherence. While the study's findings are promising, further research is needed to assess the generalizability of these results across diverse populations.
Published: Jul 15 2025, 12 ameznews.inA recent study published in *Gastroenterology* suggests that adhering to a Mediterranean or plant-based diet may significantly reduce the risk of chronic constipation, particularly among middle-aged and older adults. Chronic constipation, which affects 15%-30% of individuals aged 60 and above, can severely impact quality of life and healthcare costs. Dr. Kyle Staller, the study's senior author, emphasized the importance of dietary patterns over isolated nutrients, noting that diets rich in vegetables, nuts, and healthy fats could enhance gut function by improving the gut microbiome and reducing inflammation. Conversely, Western and inflammatory diets, high in processed foods and red meats, were associated with increased constipation risk. Experts recommend a holistic approach to gut health, including hydration, regular physical activity, and a balanced intake of whole grains, fruits, and vegetables, to promote digestive regularity and overall well-being.
Published: Jul 13 2025, 8 pmFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
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