eznews.inA recent study led by researchers from Case Western Reserve University and University Hospitals has revealed promising results in reversing cognitive decline in mouse models of advanced Alzheimer’s disease. Traditionally viewed as irreversible, Alzheimer’s may have the potential for recovery through a compound known as P7C3-A20, which restores levels of nicotinamide adenine dinucleotide (NAD+), a crucial enzyme that declines with age and is linked to the disease's progression. The study found that P7C3-A20 not only prevented further neurodegeneration but also significantly reversed brain damage, restoring cognitive function and enhancing synaptic health. While these findings challenge long-held beliefs about Alzheimer’s being a solely progressive condition, experts caution that further research is necessary before human clinical trials can commence. This approach may also mitigate risks associated with over-the-counter NAD+ supplements, offering a safer alternative for potential treatment. 
Published: Jan 10 2026, 1 pmeznews.inA recent study from Washington University School of Medicine reveals that common ADHD medications, such as Ritalin and Adderall, may function differently than previously understood. Researchers found these stimulants primarily interact with the brain’s reward and wakefulness centers, enhancing alertness and motivation rather than directly improving attention. This challenges the long-held belief that these medications primarily boost attention systems. The study, published in the journal *Cell*, analyzed brain activity in nearly 5,800 children aged 8 to 11, showing that those taking stimulants exhibited increased activity in arousal-related brain regions but not in attention circuits. Experts emphasize the importance of adequate sleep for cognitive functioning and stress that while medications can aid in task persistence, they do not replace the need for behavioral strategies and environmental adjustments. This research could reshape ADHD treatment approaches and improve understanding of how stimulant medications support individuals with the condition.
Published: Jan 10 2026, 6 ameznews.inA recent study by researchers at Newcastle University has revealed that short bursts of intense exercise, lasting just 10 to 12 minutes, may help slow the growth of colorectal cancer cells. The study involved 30 overweight adults aged 50 to 78, who underwent a high-intensity cycling session. Blood samples taken before and after the workout indicated that exercise increased levels of proteins that aid DNA repair and suppressed genes linked to rapid cell division. When cancer cells were exposed to blood serum collected post-exercise, significant changes in gene activity were observed, particularly in pathways associated with DNA repair and tumor growth. While the findings suggest potential benefits of exercise in combating colorectal cancer, experts emphasize the need for further research, particularly prospective trials, to determine the direct impact on cancer outcomes. The study highlights a promising link between physical activity and cancer prevention mechanisms, although its small sample size limits broader applicability.
Published: Jan 09 2026, 11 pmeznews.inA recent study published in *Neurology* has found a potential link between disrupted circadian rhythms and an increased risk of dementia in older adults. Researchers analyzed rest and activity rhythms (RARs) in participants averaging 79 years old, using ambulatory cardiac patches to monitor heart activity over an average of 12 days. The findings revealed that individuals with weaker rhythm strength or more fragmented rhythms faced a significantly higher risk of developing dementia, with a 54% increased risk for each standard deviation decrease in rhythm strength. Notably, those whose peak activity occurred later in the day had a 69% higher risk. While the study highlights the importance of circadian health in brain aging, experts caution that it does not establish causality and lacks diverse representation. Future research may explore interventions like light therapy to improve circadian health and potentially mitigate dementia risk.
Published: Jan 09 2026, 9 pmeznews.inResearchers from Cambridge have discovered that megestrol acetate, a synthetic progesterone often prescribed to alleviate hot flashes during menopause, can also slow the growth of estrogen-receptor positive breast tumors. The study, part of the PIONEER trial, involved 244 women with early-stage breast cancer, divided into three groups receiving varying doses of megestrol alongside the anti-estrogen drug letrozole. Findings published in *Nature Cancer* indicate that even low doses of megestrol enhanced the anti-proliferative effects of letrozole without significant differences in efficacy between dosages. This dual benefit could improve treatment adherence, crucial for long-term therapy, as adverse effects from anti-estrogen treatments can discourage compliance. However, experts caution that further studies are necessary to validate these results, as the sample size was limited and the treatment duration was short. Larger trials are needed to establish new clinical guidelines for integrating megestrol into breast cancer treatment.
Published: Jan 09 2026, 1 ameznews.inThe U.S. FDA has approved Wegovy, the first oral GLP-1 medication for weight loss, previously available only as a weekly injection. The pill, taken daily on an empty stomach, offers greater flexibility and may reduce the psychological barrier associated with self-injections, according to experts. Dr. Seth Kipnis highlighted that the pill's daily regimen could improve treatment adherence, while Dr. Devika Umashanker noted that side effects from the oral version tend to resolve more quickly than those from injections. Both formulations yield similar weight loss results—approximately 14% over 64 weeks for the pill and 15% over a year for the injection. However, the pill comes with specific contraindications, such as not being recommended for breastfeeding. Patients are encouraged to consult healthcare providers to determine which form suits them best, emphasizing that effective weight management still requires lifestyle changes alongside medication.
Published: Jan 08 2026, 9 pmeznews.inRecent studies highlight a significant connection between poor sleep and an increased risk of dementia. Research utilizing MRI scans of over 45,000 participants revealed that a weakened glymphatic system, responsible for clearing brain toxins during sleep, correlates with higher dementia risk. Additionally, individuals with moderate to severe obstructive sleep apnea (OSA) were found to have nearly double the incidence of cerebral microbleeds, which can lead to dementia and strokes. Furthermore, a study involving 2,750 participants indicated that chronic insomnia may elevate the risk of developing mild cognitive impairment or dementia by 40%, equating to approximately 3.5 years of accelerated brain aging. Experts suggest that improving cardiovascular health and ensuring quality sleep are vital for enhancing glymphatic function and potentially mitigating dementia risk. These findings underscore the importance of sleep in maintaining cognitive health as individuals age.
Published: Jan 07 2026, 11 pmeznews.inA recent review published in *Cureus* emphasizes the critical role of vitamin B12 in health, highlighting its natural and synthetic forms. Essential for DNA synthesis and cellular metabolism, vitamin B12 deficiency can lead to conditions like megaloblastic anemia, with symptoms including anemia, muscle weakness, and even paralysis if untreated. The review suggests that methylcobalamin, a natural form of B12, may be more bioavailable and better retained in the body compared to cyanocobalamin, the synthetic variant. This finding is particularly relevant for those at higher risk of deficiency, such as older adults and individuals on vegetarian or vegan diets. The authors advocate for testing B12 absorption levels to determine appropriate supplementation routes and stress the need for further research, especially in chronic illness and malabsorption contexts. They also encourage early detection of deficiencies to prevent long-term complications related to neuro and blood health.
Published: Jan 06 2026, 2 pmeznews.inThe "Dry January" campaign, launched by Alcohol Change UK in 2013, encourages participants to abstain from alcohol for the entire month, with 200,000 people signing up globally in January 2025. A recent study published in the journal *Alcohol and Alcoholism* confirms that just one month of sobriety can lead to significant physical and psychological benefits, including improved sleep, weight loss, and enhanced mood. Researchers analyzed data from over 150,000 participants, highlighting the importance of digital tools like apps and motivational content in helping individuals maintain their commitment. Lead author Megan Strowger noted that these findings underscore the cumulative toll of alcohol on health and suggest that a short-term break can facilitate long-term behavioral changes. Experts emphasize the need for social support and preparation for those considering Dry January, advising against using alcohol as a sleep aid and recommending professional help for those struggling with alcohol use.
Published: Jan 05 2026, 9 pmeznews.inA recent study published in the *European Heart Journal* highlights that cancer survivors can significantly enhance their longevity by adopting heart-healthy lifestyle habits. Researchers from Italy found that engaging in seven key behaviors—regular physical activity, a balanced diet, avoiding smoking, and managing weight, blood pressure, and cholesterol—can reduce overall mortality risk by up to 38%. The study analyzed data from 849 cancer survivors, revealing that those with higher scores on the American Heart Association's Life’s Simple 7 (LS7) metrics had better survival rates. Specifically, a one-point increase in LS7 scores correlated with a 10% decrease in cancer mortality. Experts emphasize the interconnectedness of cardiovascular health and cancer, noting that shared risk factors like obesity and inflammation can impact both conditions. The findings underscore the importance of a holistic approach to health, with physical activity being particularly crucial for improving long-term outcomes in cancer survivors.
Published: Jan 04 2026, 5 pmFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
India
World
Economy
Science
Health
Showbiz
Contact