eznews.in
A recent study published in *Nature Neuroscience* has unveiled how physical activity may protect the brain from Alzheimer’s disease at a cellular level, potentially paving the way for new prevention and treatment strategies. Researchers utilized advanced single-nuclei RNA sequencing to analyze the effects of exercise on the hippocampus, a brain region critical for memory and learning. They discovered that exercise alters the activity of immune cells known as microglia and neurovascular-associated astrocytes, enhancing their neuroprotective properties. The study also identified ATPIF1, a metabolic gene regulating energy production, as crucial for creating new neurons, which could guard against cognitive decline. Experts emphasize that while the link between exercise and brain health is well-established, this research provides deeper insights into the cellular mechanisms involved. Lifestyle changes, including increased physical activity, are recommended to reduce the risk of Alzheimer’s and slow its progression, underscoring that dementia is not an inevitable part of aging. 
Published: Jun 18 2025, 6 pmeznews.inA recent study published in JAMA Network Open suggests that regular cycling may significantly reduce the risk of dementia and Alzheimer's disease. Researchers analyzed data from nearly 480,000 participants in the U.K. Biobank, focusing on their primary modes of transportation over a median follow-up of 13 years. The findings revealed that individuals who primarily cycled or combined cycling with other transport modes had a 19% lower overall dementia risk and a 22% lower risk of Alzheimer's compared to those using non-active transport. Lead author Liangkai Chen noted that cycling's higher aerobic intensity and cognitive engagement likely enhance neuroplasticity more than walking. Furthermore, cyclists showed greater hippocampal volume, crucial for memory formation. Experts emphasize that promoting cycling as a daily transport option could be a practical strategy for improving cognitive health, particularly for older adults. However, safety and gradual progression are vital for those new to cycling.
Published: Jun 19 2025, 7 pmeznews.inA recent study from Johns Hopkins University has revealed that not all plant-based foods are heart-healthy, with unhealthy options potentially posing similar risks to heart disease as traditional animal products. Analyzing data from 7,708 participants in the National Health and Nutrition Examination Survey, researchers found that a diet high in unhealthy plant-based foods was linked to a 65% increased likelihood of elevated cardiac troponin I levels, a biomarker associated with heart attack. While healthy plant-based diets can lower heart disease risk by nearly 50%, many meat substitutes are heavily processed and high in sodium and saturated fats, which can elevate LDL cholesterol and contribute to hypertension. Experts advise consumers to choose whole foods like beans and legumes, look for options low in sodium and additives, and be cautious of processed products, emphasizing that the degree of food processing is crucial for heart health.
Published: Jun 18 2025, 1 ameznews.inRecent research has revealed a concerning connection between GLP-1 medications, such as semaglutide and tirzepatide, and an increased risk of potentially blinding eye diseases, particularly neovascular age-related macular degeneration (nAMD). The study, which analyzed health records of over 139,000 Ontario residents with diabetes, found that older adults using these drugs for more than six months had a two-fold higher risk of developing nAMD compared to those who had never used them. While the absolute risk remains low, with approximately 1 in 1,000 patients affected, researchers emphasize the need for heightened clinical awareness. Experts caution that while these medications offer significant benefits for managing diabetes and aiding weight loss, patients should be vigilant for any new vision symptoms. Further studies are needed to explore the long-term ocular safety of GLP-1 receptor agonists and confirm these findings across diverse populations.
Published: Jun 16 2025, 5 pmeznews.inA recent meta-study highlights the potential of flavan-3-ols, plant-derived compounds found in cocoa, tea, apples, and grapes, to aid in managing high blood pressure. The analysis of 145 randomized controlled studies suggests that these compounds can enhance endothelial function, which is crucial for regulating blood pressure, sometimes achieving effects comparable to hypertension medications. Although the authors do not advocate for replacing medication with flavan-3-ols, they emphasize the benefits of incorporating these foods into a heart-healthy diet. Cardiologists note that improved endothelial function can significantly reduce cardiovascular disease risk. However, the effectiveness of flavan-3-ols is highest in unprocessed forms, such as dark chocolate and pure teas, as processing can diminish their health benefits. Experts stress the importance of dietary choices in blood pressure management, advocating for a focus on whole foods to promote vascular health and reduce reliance on medications.
Published: Jun 15 2025, 6 pmeznews.inA recent study published in *Gastroenterology* suggests that a new blood test, known as the WBAIL-2 assay, could revolutionize the diagnosis of celiac disease by accurately identifying the condition without the need to provoke symptoms. Celiac disease, characterized by an abnormal immune response to gluten, typically requires patients to consume gluten and undergo biopsies for diagnosis. Involving 181 adult participants, including those on gluten-free diets, the study found that higher levels of interleukin-2, a protein linked to gluten-specific T-cells, correlated with celiac disease diagnosis. While the WBAIL-2 test showed promise, limitations include its reduced sensitivity for certain genotypes and a need for further research to establish its effectiveness across diverse populations. Experts believe it could serve as a valuable diagnostic tool alongside existing methods, potentially reducing the need for invasive procedures in the future.
Published: Jun 14 2025, 11 ameznews.inA recent study has established a significant link between late-life mood disorders (LLMDs) and an increased risk of developing dementia, highlighting the potential for mood symptoms to serve as early indicators of neurodegenerative diseases. Conducted by researchers at the National Institutes for Quantum Science and Technology in Japan, the study found that individuals with LLMDs exhibited higher levels of the proteins beta-amyloid and tau—hallmarks of Alzheimer's disease—compared to healthy controls. Notably, these abnormal protein levels can be detected up to 7.3 years before traditional dementia symptoms emerge. The findings suggest that mood disorders in older adults may reflect underlying neurodegeneration, prompting calls for a shift in clinical practice to prioritize early diagnosis and intervention. Experts emphasize the importance of treating mood symptoms not just as isolated issues but as potential indicators of broader neurological decline, thereby opening a therapeutic window for proactive management of at-risk individuals.
Published: Jun 13 2025, 6 pmeznews.inResearchers have unveiled a groundbreaking blood test capable of assessing a person's intrinsic capacity (IC), a measure of both mental and physical health that reflects aging. Previously, evaluating IC was complex and expensive, but this new method uses DNA methylation analysis from a simple drop of blood or saliva, making it accessible and non-invasive. Published in *Nature Aging*, the study indicates that this test can accurately predict all-cause mortality and overall health, with individuals showing higher IC living an average of 5.5 years longer. The findings suggest that dietary factors, such as high intake of oily fish and limited sugar consumption, positively influence IC. Experts emphasize that while the test represents a significant advancement in aging science, it should complement existing health markers. Recommendations for healthy aging include a balanced diet, regular exercise, cognitive engagement, and stress management, all aimed at maintaining both lifespan and healthspan.
Published: Jun 12 2025, 1 pmeznews.inA recent study published in *Neurology* has highlighted the impact of lifestyle choices on the risk of age-related diseases such as stroke, dementia, and late-life depression. Researchers identified a biomarker linked to aging—telomere length in white blood cells—which was found to be shorter in individuals developing these conditions. The study, involving over 356,000 adults in the UK, revealed that those with the shortest telomeres experienced a 1.5 times higher incidence of these diseases compared to those with longer telomeres. Notably, participants with shorter telomeres who maintained healthy lifestyles showed no increased risk, suggesting that adopting healthier habits can mitigate the adverse effects of biological aging. Experts emphasized the importance of understanding modifiable risk factors, as nearly 45% of dementia cases and up to 85% of strokes are linked to lifestyle choices, underscoring the potential for prevention and improved brain health even later in life.
Published: Jun 12 2025, 3 ameznews.inA recent study published in *The American Journal of Clinical Nutrition* highlights the potential benefits of flavonoid-rich foods, particularly berries, in promoting healthy aging. Conducted by researchers at the Danish Cancer Institute, the study analyzed data from over 85,000 participants aged 60 and older, revealing that higher flavonoid intake is associated with a 15% lower risk of frailty and a 12% reduced chance of poor mental health in women. While men also showed a decrease in mental health risks with increased flavonoid consumption, they did not exhibit the same benefits regarding physical function. The findings suggest that diets enriched with flavonoids could enhance strength, mobility, and overall quality of life as people age. Experts advocate for dietary modifications as a proactive approach to healthy aging, emphasizing the importance of diverse and flavorful food choices to harness the protective effects of flavonoids against age-related decline.
Published: Jun 11 2025, 4 pmFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
India
World
Economy
Science
Health
Showbiz
Contact