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A recent study conducted on mice has raised concerns about the long-term effects of ketogenic diets, which are popular for weight loss and managing obesity and diabetes. While the keto diet proved effective in inducing weight loss, it also led to increased blood lipid levels, excessive fat storage in the liver, and impaired glucose regulation. Researchers found that mice on the keto diet exhibited higher plasma lipids and glucose intolerance compared to those on a low-fat diet, which was more effective in improving metabolic health. The study, which lasted nearly a year, suggests that while the keto diet may offer short-term weight loss benefits, it could have detrimental effects on metabolic health, prompting calls for further research in humans to better understand the cardiometabolic risks associated with prolonged keto dieting. The findings highlight the need for caution when considering ketogenic diets as a long-term dietary strategy. 
Published: Sep 20 2025, 11 ameznews.inA recent commentary published in *The American Journal of Medicine* emphasizes the potential of lifestyle interventions to mitigate cognitive decline in older adults. While mild cognitive impairment (MCI) is common with aging, moderate to severe cognitive decline, including dementia, affects 10-20% of MCI cases. The study involved 2,111 older adults who participated in structured or self-guided lifestyle programs, including the MIND diet, exercise, and social engagement. Results indicated that those in structured programs showed greater cognitive improvements. Researchers urge clinicians and policymakers to promote coordinated lifestyle interventions, addressing barriers like access to nutritious food and safe exercise environments. Experts stress that while healthy choices are vital, systemic support is essential for effective implementation. Future research should focus on understanding the biological mechanisms behind these interventions, aiming for collaborative studies that could provide definitive proof of their benefits in reducing cognitive decline.
Published: Sep 23 2025, 11 pmeznews.inA recent study published in the journal *Pharmaceutics* suggests that semaglutide, the active ingredient in GLP-1 medications like Ozempic and Wegovy, may offer protective benefits against diabetic retinopathy, a potentially blinding condition affecting up to 40% of diabetics. Researchers found that retinal cells treated with semaglutide showed significantly improved survival rates and reduced markers of cell death and oxidative stress when exposed to high glucose levels. This suggests that semaglutide could not only help prevent the onset of diabetic retinopathy but may also aid in repairing existing damage. Experts, including Dr. Ioanna Anastasiou, advocate for further clinical trials to explore these protective effects in diabetic patients. Other ophthalmologists have noted consistent clinical observations of reduced retinopathy in patients using GLP-1 receptor agonists, highlighting the need for rigorous studies to evaluate their long-term efficacy in eye health.
Published: Sep 23 2025, 7 ameznews.inA recent study published in the journal *Neuron* has revealed that a high-fat diet can impair memory function in mice within just two days, highlighting a potential mechanism behind cognitive deficits associated with metabolic syndrome. Researchers found that such diets disrupt the healthy functioning of the hippocampus, particularly the dentate gyrus, crucial for memory formation. The study indicated that high-fat intake leads to overactivity in specific neurons, which are normally inhibited by glucose, resulting in memory issues. Interestingly, reintroducing glucose or inhibiting a key enzyme, pyruvate kinase M2 (PKM2), reversed these deficits. This rapid cognitive decline underscores the urgent need to understand how dietary choices impact brain health, especially as metabolic syndrome rates rise. Experts suggest that these findings may have implications for human health and future treatments for neurodegenerative diseases, emphasizing the importance of diet in cognitive function.
Published: Sep 22 2025, 8 pmeznews.inA recent study from Mass General Brigham has found that daily cocoa extract supplements may help reduce age-related inflammation, a significant factor associated with chronic diseases such as heart disease. Participants aged 60 and above who took 500 mg of cocoa extract daily for two years showed an 8% annual decrease in high-sensitivity C-reactive protein (hsCRP), a key inflammation marker linked to cardiovascular risk. The benefits were particularly evident in individuals with higher baseline inflammation levels. While the cocoa extract did not significantly affect other inflammation markers, the findings suggest potential for cocoa supplements in managing inflammation. However, experts caution that lifestyle factors remain crucial for health, and long-term safety of cocoa supplements requires further investigation. Dr. Raj Dasgupta emphasized that while the results are promising, cocoa extract should be considered an adjunct to foundational health practices rather than a primary strategy.
Published: Sep 21 2025, 6 pmeznews.inResearchers have unveiled a new eye drop formulation that may offer relief to the 1.8 billion people worldwide suffering from presbyopia, a condition characterized by age-related difficulty in seeing close objects. The study, presented at the European Society of Cataract and Refractive Surgeons Congress, highlights a combination of pilocarpine and diclofenac, an anti-inflammatory drug, which significantly improved participants' near vision, allowing them to read two to three additional lines on a Jaeger eye chart. Conducted with 766 participants, the treatment demonstrated lasting effects, with vision improvements persisting for up to two years. Lead researcher Dr. Giovanna Benozzi emphasized that this dual-action approach enhances the eye's natural focusing ability, potentially reducing reliance on glasses. While existing treatments like Vuity utilize pilocarpine alone, the addition of diclofenac aims to mitigate associated side effects. Experts advocate further research to refine these treatments and explore safer alternatives for presbyopia management.
Published: Sep 19 2025, 11 ameznews.inA recent study published in *Clinical Infectious Diseases* suggests that starting metformin, a common diabetes medication, within three months of a SARS-CoV-2 infection may significantly reduce the risk of developing long COVID by 64% in adults with obesity or overweight. The research, which analyzed data from over 624,000 participants in the UK, found that those who initiated metformin treatment were less likely to experience long-term symptoms such as fatigue and brain fog compared to non-users. While the findings are promising, experts emphasize the need for further randomized controlled trials to confirm these results. Researchers noted limitations, including potential underestimation of long COVID cases due to diagnostic coding and a lack of diversity in the study population. Despite these challenges, the study highlights metformin's potential as a low-cost intervention to mitigate long COVID risk, warranting cautious optimism among healthcare professionals.
Published: Sep 19 2025, 12 ameznews.inA recent study has reaffirmed the significant risks associated with smoking and its contribution to type 2 diabetes, confirming that this risk extends across all four subtypes of the disease. Researchers analyzed data from over 7,000 participants, including more than 3,300 with type 2 diabetes, and found that both current and former smokers were at a heightened risk of developing the condition. Specifically, heavy smokers exhibited a staggering increase in risk, with a 2.35-fold chance of developing one subtype, SIRD, and notable increases for others. The study also highlighted that smokeless tobacco products, such as snus, and vaping could similarly elevate diabetes risk, likely due to nicotine's effects on insulin resistance. While the findings are yet to be peer-reviewed, experts emphasize the need for further research into how various risk factors, including lifestyle and genetics, interact in the development of type 2 diabetes.
Published: Sep 17 2025, 5 pmeznews.inA recent study has highlighted significant differences in the cardiovascular risks associated with hormone replacement therapy (HRT) for women with type 2 diabetes. While HRT is commonly prescribed to alleviate menopause symptoms, research indicates that women using transdermal HRT patches face a 25% lower risk of developing heart disease and no increased risk of pulmonary embolism or stroke compared to those not using HRT. Conversely, those taking oral HRT were found to have double the risk of pulmonary embolism and a 21% higher chance of heart disease. The findings, based on data from over 36,000 women, suggest that transdermal HRT may be a safer option for diabetic patients. Experts emphasize the need for careful consideration of HRT forms, particularly given the heightened cardiovascular risks in women with diabetes, urging a preference for transdermal applications to mitigate potential health complications.
Published: Sep 17 2025, 1 ameznews.inA recent study has found that cannabis users are four times more likely to develop type 2 diabetes compared to non-users, based on an analysis of over 4 million individuals. Conducted by researchers at Boston Medical Center, the study identified nearly 97,000 cannabis users and matched them with over 4 million non-users, revealing a diabetes incidence of 2.2% in cannabis users versus 0.6% in non-users. While the research establishes a strong association, it does not confirm a causal link, as the mechanisms remain unclear. Potential explanations include increased insulin resistance and unhealthy eating habits often associated with cannabis use, such as the well-known "munchies." As cannabis use rises amid increasing legalization, experts emphasize the importance of understanding its health implications, suggesting that this study could inform patient care and public discourse on cannabis consumption.
Published: Sep 16 2025, 11 pmFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
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