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A recent study funded by Eli Lilly has revealed that tirzepatide, the active ingredient in the diabetes medication Mounjaro, may aid weight loss in individuals without diabetes, with participants losing an average of 13% of their body weight over six months. The study involved around 4,100 participants, predominantly female, with an average BMI of 37.1 kg/m². Notably, 74% had obesity-related complications, including dyslipidemia and hypertension. The FDA recently approved a related drug, Zepbound, for chronic weight management in adults with obesity or overweight and associated conditions. Experts emphasize the need for further research to understand the long-term effects and sustainability of weight loss with tirzepatide, as well as its potential side effects and cost implications, which can range from $349 to $1,298 monthly. Overall, the findings align with clinical observations of tirzepatide's effectiveness for weight management. 
Published: Mar 17 2025, 6 pmeznews.inA recent narrative review published in the journal *Nutrients* has highlighted a potential link between gut health and anxiety disorders, suggesting that reduced microbial diversity in the gut may exacerbate anxiety symptoms. Researchers found that individuals with anxiety often exhibit lower levels of beneficial bacteria, particularly those producing short-chain fatty acids and neurotransmitters like GABA, which are crucial for regulating stress responses. The review indicates that probiotics, especially strains like *Lactobacillus*, could help improve gut microbiota and alleviate anxiety. While some studies reported positive effects of specific probiotic strains on anxiety and related symptoms, others showed mixed results, underscoring the need for further research. Experts emphasize the importance of understanding the gut-brain connection and suggest dietary changes alongside probiotic use to promote mental well-being. However, limitations in current studies, including small sample sizes and language restrictions, highlight the need for more comprehensive research in this area.
Published: Mar 17 2025, 11 pmeznews.inA recent study published in the journal *JAMA Network Open* suggests that a lower waist-to-hip ratio (WHR) and a healthier diet during midlife may significantly enhance brain health and cognitive function in older age. Researchers analyzed data from the Whitehall II Study, focusing on participants aged 48 to 70, and found that those with higher diet quality and lower WHR exhibited better brain connectivity, particularly in the hippocampus, which is crucial for memory. The study highlights the importance of lifestyle factors, indicating that managing abdominal fat and improving diet could reduce the risk of cognitive decline and dementia. Experts emphasize that interventions during midlife can be particularly beneficial, as the aging population faces increasing rates of cognitive disorders. Nutritionists recommend dietary changes, physical activity, and social engagement as effective strategies to support cognitive health as individuals age.
Published: Mar 16 2025, 6 pmeznews.inRecent studies have identified key lifestyle factors that may reduce the risk of depression, a condition affecting a significant portion of the global population. Research published in February 2025 indicates that individuals using glucagon-like peptide-1 (GLP-1) receptor agonists, such as Ozempic for diabetes, may experience a 10% lower risk of depression compared to those on other diabetes medications. Another study suggests that daily consumption of citrus fruits, particularly oranges, could lower depression risk by up to 20%, potentially due to beneficial changes in gut microbiota. Additionally, findings from upcoming research indicate that engaging in regular moderate-to-vigorous exercise is associated with a 14% to 40% reduced likelihood of developing various neuropsychiatric diseases, including depression. Experts emphasize the importance of these modifiable factors in promoting mental health and encourage increased physical activity and dietary improvements as practical strategies to combat depression.
Published: Mar 15 2025, 7 pmeznews.inA recent study published in *JAMA Internal Medicine* suggests that replacing butter with plant-based oils, particularly olive, soybean, and canola oils, may significantly reduce the risk of premature death and cancer. Researchers analyzed data from over 200,000 participants in three long-term health studies, finding that substituting 10 grams of butter daily with an equivalent amount of plant oil was linked to a 17% decrease in overall and cancer mortality. Experts emphasize the importance of healthy fats, especially those rich in omega-3 fatty acids, for overall health. While butter is high in saturated fat and can elevate "bad" cholesterol levels, alternatives like grass-fed butter may offer some health benefits due to their higher nutrient content. Nutritionists advocate for a balanced diet that includes unprocessed fats from sources such as nuts, avocados, and fatty fish, highlighting their roles in cellular function, hormone production, and inflammation regulation.
Published: Mar 14 2025, 6 pmeznews.inThe United States is grappling with a measles outbreak, with over 220 cases reported across 12 states, prompting renewed interest in vitamin A supplements for prevention. Health experts, including infectious disease specialist Dr. Monica Gandhi and pediatrician Dr. Danelle Fisher, clarified that while vitamin A is beneficial for the immune system, it does not prevent measles. Instead, it can be useful for treating vitamin A deficiency that may arise during the illness. The Centers for Disease Control and Prevention (CDC) emphasizes vaccination as the most effective defense against measles, particularly in outbreak areas like Texas and New Mexico. Both experts caution against excessive vitamin A intake, which can lead to toxicity, and recommend that individuals ensure they meet daily intake requirements primarily through diet. Vaccination schedules suggest that children receive their first MMR vaccine dose at 12-15 months, with a follow-up at 4-6 years.
Published: Mar 14 2025, 11 ameznews.inA recent study has revealed that long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, may be linked to a reduced risk of dementia. Analyzing data from 11,745 participants in the Rotterdam Study, researchers found that those who used NSAIDs for over two years experienced a decreased risk of dementia, while shorter usage periods correlated with a slight increase in risk. The study highlights the potential role of inflammation in dementia development, suggesting that NSAIDs could mitigate this risk. However, the findings come with caveats, as the observational nature of the study limits definitive conclusions, and the sample predominantly consisted of white individuals from the Netherlands. Experts caution against recommending NSAIDs for dementia prevention without further research, noting potential side effects and the need for thorough risk-benefit analyses. Overall, the study adds to the understanding of chronic inflammation's impact on neurodegeneration and the complexities of dementia risk factors.
Published: Mar 13 2025, 12 pmeznews.inA recent study published in *JAMA Network Open* highlights the potential benefits of cardiovascular health on neurodegenerative diseases such as Alzheimer’s and dementia. Researchers found that older adults with higher scores on the American Heart Association’s Life’s Simple 7—a set of seven modifiable risk factors for heart disease—exhibited lower levels of neurofilament light chain (NfL), a biomarker linked to nerve cell damage. The study involved over 1,000 participants, predominantly from the Black community, who are at a higher risk for both cardiovascular disease and neurodegeneration. Experts emphasize that improving cardiovascular health could significantly alleviate the burden of neurodegenerative diseases, particularly in underserved populations. The findings underscore the importance of enhanced cardiovascular health education and resources, especially for Black and African American communities, to address these intertwined health issues effectively. Future research aims to explore additional biomarkers and the impact of lifestyle interventions on neurodegeneration.
Published: Mar 12 2025, 10 pmeznews.inPlastic does not biodegrade but instead breaks down into microplastics, which are microscopic particles present in every food chain and on dinner plates worldwide. Emissions of microplastics are estimated at 10 to 40 million tonnes annually, potentially doubling by 2040. Research links microplastics in blood to negative heart health impacts, and a recent study found higher concentrations in human brains, with levels increasing by 50% over eight years. While complete avoidance is impossible, experts suggest practical ways to reduce exposure, such as switching from bottled to tap water, choosing loose-leaf tea over plastic teabags, and minimizing synthetic textiles in homes. Additionally, avoiding plastic utensils and reducing the use of beauty products can help limit microplastic intake. Despite ongoing research, the health implications of microplastics remain unclear, underscoring the urgent need for further study and innovation in alternative materials.
Published: Mar 12 2025, 11 pmeznews.inA recent study published in the journal *PNAS* reveals that the timing of interventions to combat age-related cognitive decline may be crucial, with specific age windows identified as optimal for effectiveness. Researchers analyzed neuroimaging data from over 19,000 individuals, finding that brain networks begin to degrade around age 44, accelerating through the 60s and stabilizing by age 90. Lead author Dr. Lilianne Mujica-Parodi emphasized the importance of early intervention, likening brain neurons to a city reliant on a stable power supply. The study also highlighted the role of neuronal insulin resistance and the potential of ketones as an alternative energy source for aging brains. Experts, including Dr. Verna Porter and Dr. Gary Small, support the idea that a ketogenic diet may offer protective benefits against cognitive decline, suggesting further research into its long-term efficacy in at-risk populations.
Published: Mar 12 2025, 12 amFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
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