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A new study has shown promising results for a wireless retinal implant, known as the PRIMA system, designed to restore central vision in individuals suffering from geographic atrophy, an advanced form of age-related macular degeneration (AMD). Currently affecting about 8 million people globally, geographic atrophy leads to irreversible vision loss, and there is no cure available. The research involved 38 participants over 60 years old, with 32 completing the trial. Remarkably, 26 of them experienced significant improvements in visual acuity after one year of using the implant and accompanying glasses, with many regaining the ability to read at home. While the implant does not restore full vision, it offers hope for enhancing the quality of life for those affected by AMD. Experts emphasize the need for further studies to evaluate the device's long-term safety and efficacy, noting that improvements in vision can help maintain independence for aging patients. 
Published: Oct 30 2025, 5 pmeznews.inA recent study published in the Annals of Internal Medicine has revealed that the duration of walking may significantly impact cardiovascular health and mortality risk. Researchers analyzed data from 33,560 participants in the UK Biobank, all taking 8,000 steps or fewer daily. They found that individuals who accumulated their steps in longer bouts, particularly those lasting 10 minutes or more, had a notably lower risk of cardiovascular disease and all-cause mortality compared to those who walked in shorter intervals. The study highlights that about 43% of participants walked in bouts of less than five minutes, which correlated with higher health risks. While the findings suggest that longer, sustained walking sessions could enhance cardiovascular outcomes, the study's observational nature limits definitive conclusions. Experts advocate for integrating longer walking sessions into daily routines, emphasizing that even modest changes in walking patterns can yield significant health benefits.
Published: Oct 30 2025, 2 ameznews.inA recent study published in *Brain Medicine* reveals that exercise can mitigate some depressive and anxiety-like symptoms linked to high-fat, high-sugar diets typical of Western eating habits. Conducted on rats, the research found that regular physical activity helped normalize levels of metabolic hormones such as insulin and leptin, which were disrupted by unhealthy diets. While exercise reduced weight gain and improved mood, it did not fully counteract all negative effects of a poor diet, emphasizing the importance of a balanced diet alongside physical activity for optimal mental health. The study's lead author, Yvonne Nolan from University College Cork, noted that further research is necessary to confirm these findings in humans, as the results may not directly translate due to differences in physiology. The study highlights the growing concern over the mental health impacts of modern dietary patterns, compounded by sedentary lifestyles.
Published: Oct 29 2025, 12 ameznews.inA new study published in *The Lancet* suggests that GLP-1 receptor agonists, such as semaglutide, may offer heart health benefits beyond weight loss. Previous research indicated that semaglutide could reduce the risk of heart attacks, strokes, and major cardiac events by 20%. The latest findings, based on data from over 17,000 adults with cardiovascular disease, reveal that the reduction in major cardiac events is consistent regardless of weight loss. John Deanfield, the study's lead author, emphasized that semaglutide should not be viewed merely as a weight loss drug, as it may also benefit patients with modest weight or normal BMI. While waist circumference was linked to better heart health outcomes, it accounted for only a third of the cardiovascular benefits, suggesting other biochemical mechanisms at play. Experts call for further research to explore these mechanisms and the broader implications for cardiometabolic disease management.
Published: Oct 28 2025, 12 ameznews.inA new investigational drug, valiltramiprosate (ALZ-801), has shown promising results in a Phase 3 clinical trial for patients genetically predisposed to Alzheimer’s disease, particularly those with two copies of the APOE4 gene variant. This group, which represents about 15% of Alzheimer’s cases, faces heightened risks and limited treatment options. The study, involving 325 participants with mild cognitive impairment (MCI) or early Alzheimer’s, indicated that those treated with ALZ-801 experienced slower brain atrophy and reduced neurodegeneration compared to a placebo group. Although the overall trial did not meet its primary endpoint, a prespecified analysis highlighted significant benefits for MCI patients, including cognitive and functional improvements. Experts expressed cautious optimism about the drug's safety profile, especially in contrast to existing treatments that carry serious side effects. Future studies will be crucial to confirm these findings and assess the drug's potential as a safer alternative for high-risk patients.
Published: Oct 26 2025, 4 pmeznews.inA recent literature review conducted by a research team from Ponce Health Sciences University in Puerto Rico sheds light on how menopause can lead to significant structural changes in the brain. Analyzing studies published between 2020 and 2025, the team identified consistent patterns linking menopause to alterations in gray and white matter, which may explain common symptoms such as cognitive decline, mood swings, and memory issues. Notably, a decrease in gray matter volume was observed, although some studies suggest potential recovery post-menopause. Additionally, white matter hyperintensities, indicative of stress or damage in communication pathways, were more pronounced in women experiencing early menopause. Experts like Dr. Stephanie Faubion and Dr. Rhonda Voskuhl emphasized that while structural changes are evident, they do not necessarily correlate with cognitive decline or increased dementia risk. Hormone replacement therapy may offer benefits, particularly when initiated early in the menopause transition.
Published: Oct 25 2025, 6 pmeznews.inA recent study has revealed a significant link between the brain's waste clearance system, known as the glymphatic system, and the risk of dementia. Researchers analyzed MRI scans from over 45,000 participants in the UK Biobank, identifying three biomarkers related to cerebrospinal fluid (CSF) dynamics that can predict dementia risk. The findings indicate that impaired glymphatic function, influenced by cardiovascular issues such as hypertension and diabetes, increases the likelihood of developing dementia. Specifically, lower blood oxygen level-dependent CSF coupling and higher choroid plexus volume correlated with greater dementia risk, while improved CSF diffusion was associated with lower risk. Experts suggest that enhancing sleep quality and cardiovascular health could support glymphatic function, potentially reducing dementia risk. This study underscores the importance of early detection and preventive measures, advocating for routine brain imaging protocols to identify individuals at risk before cognitive symptoms manifest.
Published: Oct 24 2025, 6 pmeznews.inA recent study has revealed that the shingles vaccine may significantly reduce the risk of vascular dementia and various cardiovascular events, including heart attacks and strokes, particularly in adults aged 50 and older. Researchers analyzed data from over 38,000 participants, finding that those vaccinated against shingles experienced a 50% lower risk of vascular dementia, along with a 27% reduction in blood clot risk and a 25% decrease in heart attack and stroke likelihood. The study suggests that the vaccine's ability to mitigate inflammation could protect the brain and blood vessels, potentially offering broader health benefits beyond its primary purpose. Experts emphasize the importance of understanding these links, as they could pave the way for new preventative strategies against neurodegenerative diseases. While the findings are promising, further research is needed to establish a direct causal relationship between the vaccine and reduced dementia risk.
Published: Oct 24 2025, 12 ameznews.inA systematic review published in the *BMJ* has found that aerobic exercises, such as cycling, swimming, and walking, are particularly effective in alleviating pain and improving function for patients suffering from knee osteoarthritis, a degenerative joint disease increasingly prevalent among older adults and those with obesity. The analysis, which included data from 217 studies involving over 15,000 participants, concluded that aerobic activity enhances gait performance and quality of life, with no higher risk of adverse events compared to control groups. While other exercise modalities, including strength training and mind-body exercises, also showed benefits, the authors advocate for aerobic exercise as the primary intervention for managing knee osteoarthritis. Experts emphasize the importance of personalized exercise plans and recommend consulting healthcare professionals before starting new routines, highlighting that regular movement can significantly improve life quality for those with arthritis.
Published: Oct 23 2025, 7 ameznews.inA new study published in *The British Journal of Sports Medicine* suggests that older women can significantly reduce their risk of cardiovascular disease and mortality by taking as few as 4,000 steps on just one or two days a week. Researchers analyzed data from over 13,000 women aged around 72, finding that those who met this modest step goal lowered their cardiovascular risk by 27% and mortality risk by 26% compared to those who walked less. The findings challenge the conventional 10,000-step daily target, emphasizing that overall step volume is more critical than daily frequency. Lead author Dr. Rikuta Hamaya highlighted that such achievable goals can empower older individuals, particularly postmenopausal women, who often lead sedentary lifestyles. Experts stress the importance of accessible physical activity to improve heart health, advocating for further research on step count's impact on women with existing cardiovascular risk factors.
Published: Oct 22 2025, 9 pmFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
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