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A recent study published in *BMJ Evidence-Based Medicine* has challenged the long-held belief that light to moderate alcohol consumption may protect against dementia, suggesting that even small amounts of alcohol could increase the risk of developing the condition. Utilizing both observational and genetic analyses, researchers found that while moderate drinkers appeared to have a lower dementia risk than abstainers in observational studies, genetic data indicated a consistent increase in dementia risk with any level of alcohol intake. Lead author Dr. Anya Topiwala emphasized that the findings indicate no protective effect from low alcohol consumption, urging individuals to minimize alcohol use to reduce dementia risk. This study marks a significant shift in public health messaging, advocating for a reconsideration of alcohol consumption's role in dementia prevention, akin to strategies for reducing smoking or managing cardiovascular risks. Experts stress that the safest choice for brain health is to avoid alcohol entirely. 
Published: Sep 25 2025, 10 pmeznews.inA recent study involving over 9,000 adults has highlighted the critical role of modifiable risk factors in cardiovascular diseases, including heart attack, stroke, and heart failure, which are the leading global causes of death. The research found that more than 99% of participants who suffered these events had at least one of four key risk factors—high blood pressure, high cholesterol, high fasting glucose, or tobacco use—at unhealthy levels prior to their incidents. Notably, high blood pressure emerged as the most prevalent issue, affecting over 95% of participants in South Korea and more than 93% in the United States. The study underscores the importance of regular screening and management of these risk factors, especially since many individuals, including younger women, often remain unaware of their elevated levels. Experts advocate for heightened public health initiatives to address these preventable conditions, aiming to reduce the burden of cardiovascular diseases.
Published: Sep 29 2025, 11 pmeznews.inA recent study published in *Science Translational Medicine* reveals that rheumatoid arthritis (RA), a chronic autoimmune condition, may begin years before symptoms manifest, with elevated levels of autoantibodies detected in individuals 3-5 years prior to diagnosis. Researchers found that while 30-60% of those with these autoantibodies develop RA, many do not, complicating prevention efforts. The study characterized immune profile changes in at-risk individuals, identifying increased inflammatory proteins and immune cell activity that could signal the disease's progression. This understanding may lead to early detection and preemptive therapies, potentially preventing full-blown RA or reducing its severity. Study authors emphasize the importance of identifying at-risk individuals to avoid unnecessary treatments and side effects. The findings highlight the immune system's altered state in seemingly healthy individuals, which could pave the way for innovative approaches to managing RA and improving patient outcomes.
Published: Sep 28 2025, 5 pmeznews.inA comprehensive review published in *Biochemical Pharmacology* has found that regular coffee consumption can significantly enhance liver health, potentially reducing the risk of various liver diseases. The analysis of decades of data affirms that coffee's bioactive compounds may inhibit liver scarring and inflammation, while also elucidating the molecular pathways involved. Drinking coffee is associated with a lower incidence of conditions like fibrosis, cirrhosis, and hepatocellular carcinoma, particularly in individuals with chronic hepatitis C, who showed reduced liver damage severity with daily consumption. The review highlights coffee's antioxidant, anti-inflammatory, and antifibrotic properties, alongside its positive effects on gut microbiome balance. However, the benefits are dose-dependent, with excessive intake potentially leading to adverse effects. Experts emphasize the need for individualized consumption recommendations, particularly for those with existing health issues, while calling for further research to explore coffee's therapeutic potential in liver disease management.
Published: Sep 27 2025, 2 pmeznews.inA recent clinical trial conducted by the Karolinska Institute in Sweden has revealed that low-dose aspirin may significantly reduce the risk of colorectal cancer recurrence by 55% in patients with the PIK3 genetic mutation. The study involved 626 participants aged 31 to 80 who had undergone colorectal surgery, with half receiving 160 mg of aspirin daily and the other half a placebo for three years. Results showed a recurrence rate of 7.7% among aspirin users compared to 14.1% to 16.8% in the placebo group. The trial's findings could pave the way for personalized treatment strategies, particularly for women, whose response appeared stronger. Experts stress the importance of genetic testing for the PIK3 mutation and caution that while aspirin is generally safe, it carries risks of gastrointestinal bleeding. This study marks a significant advance in understanding how aspirin can improve survival rates in colorectal cancer patients.
Published: Sep 27 2025, 12 ameznews.inResearch published in the *British Journal of Health Psychology* has revealed that dietary choices may significantly influence the mental well-being of older adults. The study, which analyzed data from 3,103 participants in the English Longitudinal Study of Ageing, found that higher consumption of fruits, vegetables, and fish was associated with enhanced eudemonic well-being—a sense of purpose—and overall happiness. Specifically, while fruit and vegetable intake consistently correlated with greater well-being across various models, fish consumption was linked to increased happiness. However, the impact of polyunsaturated fatty acids (PUFAs) was less clear, showing weaker associations once depressive symptoms were factored in. The authors emphasized the need for further research, particularly longitudinal and cross-cultural studies, to better understand these relationships. Experts suggest that promoting healthier diets could play a crucial role in improving psychological well-being among older adults.
Published: Sep 26 2025, 8 pmeznews.inA recent study published in *Clinical Nutrition* suggests that the Green Mediterranean diet, which emphasizes polyphenol-rich foods like green tea, Mankai (duckweed), and walnuts, may slow brain aging more effectively than traditional Mediterranean diets. Previous research has linked the Mediterranean diet to improved brain health and a reduced risk of dementia. The study analyzed data from 300 participants over 18 months, measuring proteins in their blood serum associated with aging. Notably, those following the Green Mediterranean diet showed lower levels of Galectin-9 and Decorin, proteins linked to accelerated brain aging. Experts emphasize the need for further research to confirm these findings and explore how diet interacts with other lifestyle factors affecting brain health. Nutritionists recommend simple dietary swaps, such as substituting meat with legumes and increasing green tea consumption, to incorporate elements of the Green Mediterranean diet into daily life.
Published: Sep 25 2025, 11 pmeznews.inA recent study published in PLOS One emphasizes that it is never too late for older adults, defined as those aged 60 and above, to improve their health through lifestyle changes. As the global population of older adults is projected to rise from 12% in 2015 to 22% by 2050, the study analyzed data from over 8,000 participants in the Canadian Longitudinal Study on Aging. Researchers found that those who engaged in healthy practices—such as regular physical activity, non-smoking, adequate sleep, and management of chronic conditions—significantly increased their chances of achieving optimal well-being over three years. The findings counter the prevailing narrative of inevitable decline with aging, highlighting the importance of early interventions and support programs. Experts stress that fostering resilience and lifestyle modifications can lead to improved quality of life, ultimately benefiting both individuals and society at large.
Published: Sep 25 2025, 1 ameznews.inA recent commentary published in *The American Journal of Medicine* emphasizes the potential of lifestyle interventions to mitigate cognitive decline in older adults. While mild cognitive impairment (MCI) is common with aging, moderate to severe cognitive decline, including dementia, affects 10-20% of MCI cases. The study involved 2,111 older adults who participated in structured or self-guided lifestyle programs, including the MIND diet, exercise, and social engagement. Results indicated that those in structured programs showed greater cognitive improvements. Researchers urge clinicians and policymakers to promote coordinated lifestyle interventions, addressing barriers like access to nutritious food and safe exercise environments. Experts stress that while healthy choices are vital, systemic support is essential for effective implementation. Future research should focus on understanding the biological mechanisms behind these interventions, aiming for collaborative studies that could provide definitive proof of their benefits in reducing cognitive decline.
Published: Sep 23 2025, 11 pmeznews.inA recent study published in the journal *Pharmaceutics* suggests that semaglutide, the active ingredient in GLP-1 medications like Ozempic and Wegovy, may offer protective benefits against diabetic retinopathy, a potentially blinding condition affecting up to 40% of diabetics. Researchers found that retinal cells treated with semaglutide showed significantly improved survival rates and reduced markers of cell death and oxidative stress when exposed to high glucose levels. This suggests that semaglutide could not only help prevent the onset of diabetic retinopathy but may also aid in repairing existing damage. Experts, including Dr. Ioanna Anastasiou, advocate for further clinical trials to explore these protective effects in diabetic patients. Other ophthalmologists have noted consistent clinical observations of reduced retinopathy in patients using GLP-1 receptor agonists, highlighting the need for rigorous studies to evaluate their long-term efficacy in eye health.
Published: Sep 23 2025, 7 amFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
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