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Doctors at City of Hope Hospital in California have announced that a 66-year-old patient has achieved long-term remission from HIV, marking the fourth such case globally. The patient, who had lived with HIV for 31 years and was also battling leukemia, received stem cells from a donor with a rare genetic mutation. This treatment, administered 3.5 years ago, makes him the oldest individual to enter remission for both conditions. Despite the absence of a definitive cure for HIV, antiretroviral drugs can suppress the virus to undetectable levels, allowing patients to lead healthy lives. The patient, who wishes to remain anonymous, stopped his antiretroviral therapy 17 months ago without any resurgence of the virus. Dr. Jana Dickter, who will present the findings at the AIDS 2022 conference, emphasized the potential for less intensive chemotherapy regimens for older patients with HIV and blood cancers, based on this case. 
Published: Dec 23 2025, 3 ameznews.inIn a surprising twist of history, chainsaws were originally invented as surgical tools to assist in childbirth, specifically during a procedure called symphysiotomy. This operation, which involved severing the cartilage between pelvic bones to widen the pelvis, was performed before the advent of modern anesthetics and antiseptics, making childbirth a perilous endeavor. In the late 18th century, Scottish doctors John Aitken and James Jeffray developed the first chainsaw, a hand-cranked device designed to expedite this risky procedure. The chainsaw's design evolved, and by 1905, it was repurposed for logging, revolutionizing the industry. While the initial use of chainsaws in childbirth may seem horrific, it represented a significant advancement in medical practice at the time. Today, chainsaws are synonymous with forestry, with the world's largest, measuring nearly 23 feet, serving as a testament to their evolution from surgical tool to logging equipment.
Published: Dec 25 2025, 10 pmeznews.inScientists involved in the 4D Nucleome Project have unveiled a groundbreaking 3D map of the human genome, illustrating not only its structure but also the dynamic interactions between its components over time. This advancement follows the completion of the Human Genome Project over two decades ago, which provided a linear sequence of genetic code. The new model reveals that the genome is not merely a static blueprint but a complex, folding entity where genes interact, influencing cell identity and disease development. Researchers have catalogued over 140,000 looping interactions in human embryonic stem cells and fibroblasts, enhancing understanding of gene regulation. The project aims to inform future studies on genetic variants and their roles in diseases like cancer, potentially leading to innovative diagnostic tools and therapies. As Feng Yue, a professor at Northwestern University, noted, understanding these 3D structures could revolutionize approaches to targeting genetic alterations in various cancers.
Published: Dec 25 2025, 5 pmeznews.inIn a significant breakthrough in HIV research, scientists have announced that a second individual, known as the "London patient," has been functionally cured of HIV-1, as detailed in a new report published in *The Lancet HIV*. Following a stem cell transplant from donors with an HIV-resistant gene, the patient has remained in remission for 30 months without antiretroviral therapy, leading researchers to express high confidence in the likelihood of a life-long cure. This case mirrors that of the "Berlin patient," who was cured in 2008 using a similar method. While remnants of the virus's DNA persist in the London patient's tissue, researchers describe these as harmless "fossils." However, experts caution that such high-risk treatments are only suitable for patients with life-threatening cancers and are not a widespread solution for all HIV patients, who can effectively manage the virus with existing medications. The London patient, Adam Castillejo, aims to inspire hope through his story.
Published: Dec 25 2025, 6 pmeznews.inIn a recently resurfaced video, Kirsten Carlson, a woman who experiences life without an inner monologue, shared insights into how this phenomenon shapes her daily experiences. Speaking to the YouTube channel PA Struggles, Carlson explained that instead of an internal voice, she visualizes information as organized files in her mind, which she can access when needed. This contrasts with the experiences of many others, who report a mix of inner dialogue and other thought processes. Carlson noted her attempts to engage in self-talk since discovering that inner monologues exist, often resulting in her speaking aloud instead. Scientific studies indicate that while most people experience some form of inner speech, there is significant variability; a 2008 study found that only 26% of participants reported inwardly talking to themselves at any given moment, highlighting the diverse ways individuals process thoughts.
Published: Dec 25 2025, 8 pmeznews.inDoctors have announced that a man known as the "Geneva Patient" has achieved long-term remission from HIV, marking him as the sixth individual effectively "cured" of the virus. This breakthrough was revealed by the Hôpitaux Universitaires de Genève and the Institut Pasteur ahead of the International AIDS Conference in Brisbane, Australia. Unlike previous cases where patients received bone marrow transplants from donors with a CCR5 gene mutation that blocks HIV, the Geneva Patient's donor did not carry this mutation. After living with HIV since the early 1990s and undergoing a stem cell transplant in 2018 for leukemia, the patient was weaned off antiretroviral therapy in November 2021. Remarkably, 20 months later, no traces of the virus were found in his body. While this case offers hope for future HIV treatments, researchers caution that widespread cures remain elusive.
Published: Dec 23 2025, 2 ameznews.inA recent study by Professor Nathan MacDonald from the University of Cambridge highlights the profound impact of a 500-year-old Bible map, created by Lucas Cranach the Elder, on modern perceptions of geography and political borders. Printed in 1525, the map was notably flawed, depicting the Mediterranean to the east of Palestine, yet it played a pivotal role in shaping how people understood the Bible and the world. As access to Bibles increased in the 17th century, this map contributed to the notion of political borders as definitive truths rather than symbolic representations. MacDonald argues that the intertwining of biblical narratives with emerging political theories transformed societal views on territory and governance. Today, many still view political boundaries through a biblical lens, raising concerns about the simplification of ancient texts in contemporary ideological contexts. The study is published in The Journal of Theological Studies.
Published: Dec 25 2025, 7 pmeznews.inThe _Vasa_, a symbol of Swedish naval ambition, tragically sank on its maiden voyage on August 10, 1628, just minutes after setting sail. Designed by shipbuilder Henrik Hybertsson, the vessel was top-heavy and unstable, leading to its quick demise when a gust of wind caused it to tip and water flooded through open gunports. Of the approximately 150 people aboard, 30 perished. The wreck lay undisturbed for 333 years until marine engineer Anders Franzén rediscovered it in 1956, leading to a complex salvage operation that successfully raised the ship in 1961. Remarkably preserved in cold water, the _Vasa_ now resides in the Vasa Museum, showcasing its intricate design and artifacts, including the remains of 17 individuals. However, concerns remain about the ship's preservation, as its wood has weakened significantly since recovery, prompting ongoing efforts to ensure its survival for future generations.
Published: Dec 24 2025, 9 pmeznews.inOnline riddles claiming to determine if someone is a psychopath have gained popularity, but experts warn that such simplistic assessments are misleading. Two notorious examples include a scenario involving a woman who kills her sister after meeting a man at her mother's funeral, and a moral dilemma about sacrificing one person to save five. While these riddles suggest that certain responses indicate psychopathy, researchers emphasize that psychopathy is a complex personality disorder that cannot be accurately diagnosed through a single question. Craig S. Neumann, a psychology professor, notes that psychopathic traits exist on a spectrum, encompassing characteristics like lack of empathy and emotional detachment. The definition of psychopathy remains debated, and it is not yet classified as a distinct disorder. As research continues, the understanding of psychopathy evolves, highlighting the need for nuanced perspectives rather than binary classifications.
Published: Dec 25 2025, 12 pmeznews.inOn January 3, 2026, Earth will reach perihelion, its closest point to the Sun, approximately 2.5 million kilometers (1.5 million miles) nearer than at aphelion, the farthest point. This phenomenon can be perplexing for those in the Northern Hemisphere, where winter coincides with this closest approach, while the Southern Hemisphere experiences summer. The seasons are dictated by Earth's axial tilt of 23.5 degrees, not its distance from the Sun, which varies by only about 3 percent throughout the year. Earth's elliptical orbit, influenced by the gravitational pull of gas giants like Jupiter and Saturn, results in slight variations in distance and season lengths. Currently, Northern Hemisphere summers are about 4.5 days longer than winters, but this will change over time as the timing of perihelion and aphelion shifts. In 6,430 CE, perihelion will align with the March equinox, illustrating the dynamic nature of Earth's orbit.
Published: Dec 25 2025, 5 amFor the fastest, latest, not so wokest news, 'experts say' you need to visit Eznews
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